Glycosaminoglycan chains of biglycan promote bone morphogenetic protein-4-induced osteoblast differentiation
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چکیده
منابع مشابه
Glycosaminoglycan chains of biglycan promote bone morphogenetic protein-4-induced osteoblast differentiation.
Biglycan (BGN) has been reported to promote bone morphogenetic protein-4 (BMP-4) stimulated osteoblastic differentiation. However, the underlying mechanism has yet to be fully elucidated. The glycosaminoglycan (GAG) chains of BGN have a variety of biological functions. In the present study, we explored the potential role of the GAG chains of BGN in promoting BMP-4-induced osteoblast differentia...
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Patricia A. Miguez Biglycan Modulation of Bone Morphogenetic Protein-2 Functions (Under the direction of Professor Mitsuo Yamauchi) Biglycan (BGN) is a proteoglycan found in high abundance in mineralized tissues. Study of its functions has unveiled roles in collagen organization (i.e. type VI), osteoblast differentiation, matrix mineralization, inflammatory processes, etc. Recently, we have rep...
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ژورنال
عنوان ژورنال: International Journal of Molecular Medicine
سال: 2012
ISSN: 1107-3756,1791-244X
DOI: 10.3892/ijmm.2012.1091